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In several preclinical studies, ASX has been shown to have an indirect antioxidant effect by activating the transcription factor nuclear factor erythroid 2-related factor 2 and increasing the expression of its antioxidant target genes, including phase II biotransformation enzymes [69,70,71,72,73,74]

Turner Award

Through a spokesperson, the FDA said it generally does not comment on litigation or compliance matters and referred to inspection documents posted on its website

To evaluate the safety of ACE for tumor therapy, we further conducted acute toxicology experiments in which mice were orally administered ACE (50 mg/kg) daily for 10 days

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DPP-IV-Resistant, Long-Acting Oxyntomodulin Derivatives