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showed appendectomy was associated with a lower risk of CC (HR = 0.90, 95% CI = 0.810.99) and distal CC (HR = 0.77, 95% CI = 0.650.90) ( Several limitations to this study deserve our attention: First, this study mainly included GWAS summary data of Europeans, and the results may not be extended to other ethnic groups

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However, there was a significant difference in Group 2 between insulin and glucagon cells with strong GPX1 staining ( p = 0.03)

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