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Our findings preliminarily support the potential of the proBDNF/BDNF ratio as a phase-specific marker of neuroplasticity in CUD [4]

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Supplementary Figure S2 shows that HaCaT cells had an apparent cytotoxic effect with the treatment of 1,600 M of H 2 O 2 , while HFF-1 showed obvious cytotoxicity at 800 M of H 2 O 2 after 2 h incubation

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