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This process can either suppress immunity or improve host defense during infections, depending on the nature of cell death [44]

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Stress and certain nutrient deficiencies may also contribute to low stomach acid levels

The PT is rich in mitochondria since it needs ATP production for reabsorption and transportation against gradients 292,293,294

Whilst extracellular A plaques, NFT, inflammation in the form or reactive astrocytes and microglia, and neuronal loss are all consistent pathological features of AD, a mechanistic link between these factors is yet to be clarified

EV4B,C), consistent with previous reports in other Leishmania models (Lee et al, 2020