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On the contrary, it has been demonstrated that, due to its ability to facilitate transport of long-chain fatty acids into the mitochondrial matrix, l-carnitine is able to trigger cardioprotective effects by reducing inflammation, oxidative stress and necrosis of cardiomyocytes [36]

Heme is necessary to assemble cytosolic and nuclear proteins that contain ironsulfur groups (Dietz et al., 2021)

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In conducting this review, we followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to ensure rigorous methodology and transparent presentation of data

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