topiramate vs tirzepatide + Semaglutide Together: Safety & Efficacy Guide – PlexusDx Topamax - Weight Loss, Migraine

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Regarding lipid profiles in patients receiving tirzepatide or semaglutide in the SURPASS-2 trial, there were reductions in triglycerides that were greater with tirzepatide than semaglutide, as well as improvements in high-density lipoprotein cholesterol and significant reductions in very low-density lipoprotein cholesterol

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The number of studies examining newer medicines like semaglutide and tirzepatide remains relatively small, and follow-up durations after stopping medicines were generally short, meaning some estimates are modelled projections beyond observed follow-up

studies have shown that it also has a certain protective effect on reducing the incidence of cardiovascular disease in some high-risk groups