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Oxidative stress is thought to play a major role in neurodegeneration caused by traumatic brain injury and exposure to neurotoxins, and may be a factor in the course of many chronic neurodegenerative diseases, including Alzheimer disease (AD)

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10.5217/ir.2014.12.2.103 [DOI] [PMC free article] [PubMed] [Google Scholar] 17.Xue JC, Yuan S, Meng H, Hou XT, Li J, Zhang HM, Chen LL, Zhang CH, Zhang QG

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However, there are also a variety of non-motor symptoms that can occur, which can have a significant impact on the patients quality of life