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For diarrhea, focus on the BRAT diet (bananas, rice, applesauce, toast) during acute episodes

Lack of IR expression resulted in abnormal differentiation of cultured murine skin keratinocytes, as demonstrated by a decrease in the expression of early skin differentiation markers

( Amino acids affect the synthesis of lipids, glutathione, nucleotides, etc

doi: 10.1016/j.redox.2020.101670 52 WangYQChangSYWuQGouYJJiaLCuiYMet al

Other examples include the recently reported ability of nuclear IGF-1R to drive chemotherapy resistance in various types of cancer, and notably, through interactions with nuclear mitotic apparatus (NuMA) protein and regulating p53binding protein 1 (53BP1) dependent DNA doublestrand break repair in colorectal cancer (40)

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