This is different from GLP-1s mechanism, which primarily reduces the drive to eat and the reward value of food through hypothalamic and mesolimbic circuits
Glyceollins also enhanced GLP-1
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2 Interestingly, in an animal model of pancreatitis, it was recently found that, contrary to the present data, GLP1Rs were increased in acini and ducts
GLP-1 receptor activation enhances glucose-dependent insulin secretion, suppresses inappropriate glucagon release, slows gastric emptying, and reduces appetite through central nervous system effects