Medeiros Dantas, J
doi: 10.1164/rccm.202108-1903LE 202 VermeulenRCWKurkRMVisserFCSluiterWScholteHR
seven mutual residues in MRP1 and MRP7 that bind fluoxetine: M339/G299, R378/A338, A587/A542, I591/M546, E1204/Q1156, Q1239/S1193, and T1241/T1195
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Oxidative stress can cause toxic effects by damaging proteins and DNA in the cell and disrupting normal cell signaling
In all models, the following fixed covariates were entered: assigned treatment (investigational product or placebo), baseline measurement of the outcome of interest, visit (day 14 1 day or day 28 1 day), visit in interaction with treatment, period (period 1 or period 2), sex and, for MIDT outcomes, incentive level