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These results provide us confidence to initiate MARITIME, a Phase III program across obesity and a number of related conditions, providing a unique potential new treatment option for patients. MariTide was well-tolerated across all dosage groups, with the most common side effects being mild gastrointestinal symptoms, such as nausea and diarrhea, which were largely mild, transient and primarily associated with the first dose, according to Amgen
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We are still early in understanding exactly which patients benefit most, how much of the effect is independent of weight loss, and how GLP-1s compare with other metabolic interventions
