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The advantages of intranasal administration, including reduced dosage loss, enhanced precision in drug delivery, and expedited brain access, were used to show that GHK-Cu was able to mitigate cognitive impairment and features of AD neuropathology

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Western blotting indeed confirmed the presence of DDX3X in extracellular virions but not on the nuclear capsids (Fig

NCTC1469 cells, a normal mouse hepatocyte cell line, were obtained from the American Type Culture Collection and were cultured in DMEM containing 10% (v/v) fetal horse serum, 2 mM glutamine, 5 U/mL penicillin, and 50 g/mL streptomycin at 37 C in a humidified O 2 /CO 2 (19:1) atmosphere