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Furthermore, comprehensive reviews of antioxidant therapies have emphasized the relevance of catalase and other ROS-scavenging enzymes in mitigating the molecular cascades triggered by oxidative and nitrosative stress during sepsis (Kumar et al., 2022

Mice deficient solely in GPx-1 do not develop cancer

Targeting BRD4 resulted in significant downregulation in the expression of MYC proto-oncogene, restraining colon cancer progression

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In mammals, HRD1 mediates K48-linked degradation of BMAL1, regulating transcriptional activity of downstream circadian genes (Guo et al., 2020)

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