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As kidney function deteriorates, patients may experience fatigue, nausea, vomiting, loss of appetite, and difficulty concentrating (Liyanage et al., 2022)

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(1993) investigated IGF-1 LR3 in animal models and demonstrated that its reduced IGFBP binding resulted in enhanced bioactivity compared to native IGF-1 at equivalent doses [2]

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The antifungal activity and mechanism of dehydroabietic acid against alternaria alternata causing poplar leaf spot