In elderly individuals, circadian rhythms as well as sleep-wake regulation are weakened, leading to phase advances, decreased ability to adjust to phase shifts, and reduced amplitude of circadian rhythms (Duffy et al., 2015)
All individuals start at the .25mg
But, the chance of long-term success is much higher than abruptly stopping a medication with no backup
Marathe CS, Horowitz M, Trahair LG, Wishart JM, Bound M, Lange K, et al
Finally, psychological factors including anxiety about starting a new medication, concerns about side effects, or the stress of managing a chronic condition can manifest as or worsen perceived fatigue
Many are patients with genuine health conditions that, until two years ago, relied on several of the peptides in question to just live normal lives