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Translational concordance is strong: zebrafish SLC52A3 knock-down and SLC52A3 / mice recapitulate hearing loss, ataxia and early death, all of which improve with systemic riboflavin supplementation (17, 18)

Nizari S, Basalay M, Chapman P, Korte N, Korsak A, Christie IN, et al

Needle-phobia is real, and the discomfort of ongoing needle injections is a real barrier for many people who require ongoing medical care

As a result, when the vial thaws, the benzyl alcohol is no longer evenly distributed throughout the solution you may end up with concentrated pockets and diluted areas