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This is the second pathway tirzepatide adds

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Whilst GLP-1 analogues are large peptide molecules that theoretically have limited transfer into milk, animal studies have demonstrated their presence in the milk of lactating rats

Mechanistically, the accumulation of serotonin due to MAO-A blockade by MB can overstimulate serotonin receptors, resulting in agitation, hyperthermia, tremor, and other symptoms of serotonin toxicity

Dosing Frequency: Weekly vs