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In fertility and early embryonic development studies, male and female rats were administered twice weekly subcutaneous doses of 0.5, 1.5, or 3 mg/kg (0.3-, 1-, and 2-fold and 0.3-, 0.9-, and 2-fold, respectively, the MRHD of 15 mg once weekly based on AUC)

Notably, the manufacturer has filed with the FDA for a second indication to reduce MACE in adults with T2D and established cardiovascular disease

Clinical evidence, including data on GLP-1 class medications, shows that most patients who stop without behavioral support and monitoring regain a substantial portion of lost weight within 12 months

The main difference between the two is how you take them - as a daily pill versus a weekly shot

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