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Unlike medications requiring therapeutic drug monitoring (such as immunosuppressants or certain antibiotics), tirzepatide dosing is standardized based on clinical response and tolerability rather than serum concentrations
Antibody therapeutics and immunoregulation in cancer and autoimmune disease
however, delayed gastric emptying, called gastroparesis, and increased colonic transit time are common side effects of these medications that raise concerns about the possibility of aspiration pneumonia following endoscopy
Important safety considerations include the risk of acute pancreatitis (seek urgent medical attention for severe, persistent abdominal pain), gallbladder disease, and potential worsening of diabetic retinopathy, particularly in patients with pre-existing retinopathy who experience rapid improvement in blood glucose control
Ali agrees there are pluses and minuses for both forms of GLP-1 drugs
Igosheva N, Abramov AY, Poston L, Eckert JJ, Fleming TP, Duchen MR, McConnell J: Maternal diet-induced obesity alters mitochondrial activity and redox status in mouse oocytes and zygotes
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