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ZXGD reversed apoptosis resistance and augmented proliferation of PASMCs in vitro To investigate pharmacological activity of ZXGD on PASMCs so as to explore its therapeutic potential on pulmonary vascular remodeling, we detected effect of ZXGD on PASMCs exposed to PDGF-BB by examining cell viability, proliferation and apoptotic proteins

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N Engl J Med 335: 453-461

Zhang Z, Zhai H, Geng J, Yu R, Ren H, Fan H, et al

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Possible Side Effects Due to a lack of research, little is known about the side effects of using glutathione supplements