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References: [1] GEORGE KOSSOY

Therapy 7 , 661668 (2010)

The glucose spike and the crash that follows it disappear

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Historical reason: the original 503A and 503B compounding pharmacies that started compounding semaglutide in 2022 used B12 as a "marker" so patients and providers could visually distinguish their compounded product from FDA-approved Ozempic, which is always clear