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Eberhart BL, Ewald DK, Sanders RA, Tallmadge DH, Zyzak DV, Strothers MA (2005) Quantitation of acrylamide in food products by liquid chromatography/mass spectrometry

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The skin barrier physically prevents most weight-loss compounds (including berberine at therapeutic doses) from being absorbed in useful amounts

And that was the first time I was able to say as an obesity medicine specialist that if I give you this drug, I can likely improve your life and reduce your chance of dying from cardiovascular disease

These hypotheses remain research questions, not final conclusions

Blood pressure and heart rate should be monitored, particularly in patients with pre-existing cardiovascular conditions, which may be more prevalent in those with longstanding hypothyroidism