We treated with concentrations of SCLA compounds and derived alkyne probes (Supplementary Table 3) at which there was a strong senolytic effect but no cytotoxic effects in non-senescent cells (Fig
12 Pathophysiology and signaling pathways involved T2D, usually accompanied by other manifestations of MDS, is a complex metabolic disease with multiple underlying mechanisms not fully understood, while IR and cell dysfunction are two core pathophysiological mechanisms 13,14 (Fig
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Regulatory Toxicology and Pharmacology
[DOI] [PubMed] [Google Scholar] 148.Ferreira A.M., Ciriolo M.R., Marcocci L., Rotilio G
