irritation is a sign to pull back
PMCID: PMC8816411
Before supplementing, consult your doctor about appropriate dosing if you are taking a medication that impairs absorption (such as PPIs or diuretics) or if you have a condition that impairs excretion (such as kidney disease)
Nat Rev Mol Cell Biol (2012) 13:61630
104 Tryptophan and its derivative, 5-hydroxytryptophan (5-HTP), have been used to treat depression, anxiety, and sleep disorders, 103,105 and higher dietary tryptophan intake was linked to lower risk of depression and increased self-reported sleep duration in an observational study with 29,687 participants
If the balance of gut bacteria is disrupted during glutathione supplementation, it could potentially lead to bloating and other digestive issues