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Placental ischemia, as the causative factor for preeclampsia, leads to dysfunction of maternal vascular endothelium causing reduced synthesis of vasodilators and increased synthesis of endothelin, a potent vasoconstrictor
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Eur J Pharmacol (2011) 650(23):7037.10.1016/j.ejphar.2010.10.062 135 MuJWoodsJZhouYPRoyRSLiZZycbandEet alChronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic beta-cell mass and function in a rodent model of type 2 diabetes
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