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The European Medicines Agencys safety committee concluded that semaglutide, the active ingredient in Ozempic, Wegovy, and Rybelsus, may rarely cause non-arteritic anterior ischemic optic neuropathy (NAION)

Design, synthesis, structure-activity relationships, and docking studies of 1-(gamma-1,2,3-triazol substituted prolyl)-(S)-3,3-difluoropyrrolidines as a novel series of potent and selective dipeptidyl peptidase-4 inhibitors

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It has been demonstrated that the activation of arcuate POMC neurons by liraglutide involves the opening of the transient receptor potential classical 5 (TRPC5) channel, a key member of the NSC channel family [6]

the decoy receptor may have a higher affinity for VEGF than the signaling receptor, which is indeed the case