GLP-1RAs are useful tools for the treatment of T2DM, especially for patients aiming weight loss or to hypoglycaemia

Why IVF increases APD risk IVF protocols commonly require progesterone injections, suppositories, or oral formulations at doses much higher than those produced during a natural cycle Exogenous progesterone bypasses the bodys normal regulatory mechanisms, increasing the likelihood of mast cell activation and histamine release Repeated exposure during fertility treatment may unmask previously undiagnosed APD or worsen existing symptoms When progesterone desensitization is used Desensitization protocols may be recommended before or during IVF for individuals with known or suspected APD These protocols involve carefully supervised, incremental exposure to progesterone to reduce immune reactivity Desensitization is most often used when progesterone cannot be avoided, such as during luteal support or early pregnancy Role of antihistamines and corticosteroids during IVF Antihistamines (such as H1 and H2 blockers) are commonly used to blunt histamine-mediated symptoms during progesterone exposure Short-term corticosteroids may be prescribed to control severe inflammatory or allergic reactions during treatment cycles These medications do not treat the underlying hypersensitivity but can help protect patient safety and treatment continuity In some cases, clinicians may also consider antioxidant support such as NAC to help manage inflammatory stress during fertility treatment or pregnancy , though this should always be individualized

People who are pregnant or nursing During pregnancy, the demand for B vitamins, particularly B12 and folate, grows
Disclosure of interest: All authors: nothing to disclose Poster session I - DIAGNOSIS / ETIOLOGY 04.00 - DIAGNOSIS / ETIOLOGY - 04.01 - DIAGNOSIS/INVESTIGATION OF STROKE ETIOLOGY P327 - ESOC25-999 MICROEMBOLIC SIGNAL DETECTION: A 5-YEAR EXPERIENCE AT A GERMAN NEUROVASKULAR CENTER Lili Laura Bruta 1 , Irena Kovacic 1 , David Pollinger 2 , David Olmes 2 , Ralf Linker 2 , Felix Schlachetzki 1 1 Center for Vascular Neurology and Intensive Care Medicine (Center II) at the Department of Neurology at the University of Regensburg, Regensburg, Germany, 2 Department of Neurology at the University of Regensburg, Regensburg, Germany Background and Aims: Microembolic signal detection (MES-D) is a potent sonographic biomarker for increased stroke risk but still has no widespread impact on stroke therapy
[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Park W.-C., Chang J.-H
AT4 receptor structure-binding relationship: angiotensin IV analogues