Maintenance schedule Month 1-2 : Stay at current dose, assess stability Month 3-4 : Reduce by 2.5mg, monitor weight Month 5-6 : Reduce again if weight stable Long-term : Minimum dose that prevents regain Coming off tirzepatide Not recommended : Abruptly stopping often leads to rapid weight regain
[PubMed] [Google Scholar] 26.Lockwood CJ, Kuczynski E
Data for weight and HbA 1c were recorded at 0, 3, 6, and 12 months following initial medication changes after referral to our endocrine clinics (controls) or after start of either GLP-1 analog or SGLT-2 inhibitor
Healthcare providers consider factors such as the patient's body weight, other medications they may be taking, and overall health status when determining the appropriate dosage regimen
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