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Microdosing GLP-1 receptor agonists like semaglutide and tirzepatide represents a promising frontier for patients seeking metabolic benefits with improved tolerability

Tumor size closely tracked with body fat and liver fat, suggesting that metabolic improvements themselves may help slow tumor growth

That is to say, the benefit is tightly linked to continued treatment, and obesity behaves as a chronic disease rather than one amenable to short-course intervention

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Brain imaging studies have shown structural and functional alterations in depression, particularly the decreased volume of the hippocampus and the subgenual and anterior cingulate cortex of the prefrontal cortex (134, 135)

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