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Recent progress in hydrophobic ion-pairing and lipid-based drug delivery systems for enhanced oral delivery of biopharmaceuticals
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The phase 3b trial, led by Weill Cornell Medicine and NewYork-Presbyterian, enrolled patients from the SURMOUNT-5 study and represents the first head-to-head data on longer-term weight maintenance using an oral GLP-1 following injectable therapy
Physicians most frequently cited GI side effectsparticularly persistent nausea and vomitingas the primary reasons for discontinuation
The role of endogenous GLP-1 in heat sensitivity was demonstrated by the observation that the intraperitoneal glucose-treated group presented a decrease in heat sensitivity compared with the vehicle-treated group (Fig
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