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White matter injury after intracerebral hemorrhage: pathophysiology and therapeutic strategies

Neurotoxic signaling from motor neurons appears to stimulate cells to produce reactive oxygen species and pro-inflammatory cytokines, causing motor neuron stress, cell damage, and initiating a self-propagating cycle of progressive cell death [18, 41, 42]

These types of trials are the gold standard when it comes to safety and the ability to determine whether a treatment is effective or not

Younger, healthy individuals with intact glutathione synthesis pathways may see less additional benefit from supplementation

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