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In a 2022 study, scientists concluded that MOTS-c plays an essential physiological role in mitochondrial function and appears to be a promising therapy for [ME/CFS] associated fatigue. This means MOTS-c could potentially help restore cellular energy production in conditions where it is deficient, thereby improving stamina and reducing chronic fatigue
The primary supplement gives you an immediate spike in blood levels, while L-Citrulline acts as a slow-release mechanism, keeping those levels elevated for up to 12 hours
others discontinue due to nausea or side effects
doi: 10.3892/or.2020.7890 15 SpechtEKaemmererDSngerJWirtzRMSchulzSLuppA
Journal of the American Chemical Society 137 , 21282136, (2015)
In 2023, the class received approval for reducing cardiovascular risk
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