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An additional post-hoc sensitivity analysis was performed by excluding the ITCA 650 trial [9] to investigate both primary and secondary outcomes to validate the robustness of the pooled analysis (Supplementary Appendix D)

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Keep out of the sight and reach of children PRINCIPAL DISPLAY PANEL - Kit Carton 1 x 3.5 mL Prefilled Cartridge 1 On-Body Infusor NDC 72511-770-01 AMGEN Repatha Pushtronex system (evolocumab) On-Body Infusor and Prefilled Cartridge 420 mg/3.5 mL For Subcutaneous Use Only Single-Dose Only Sterile Solution No Preservative Store refrigerated at 2C to 8C (36F to 46F)

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Pfizer (eliminated): The discontinuation of danuglipron in April 2025 eliminated the most advanced competing oral small-molecule GLP-1 program