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In rodent studies, animals with greater GLUT4 expression display heightened insulin sensitivity, whereas those with reduced GLUT4 levels demonstrate impaired insulin signaling

Therefore, researchers are actively investigating the potential of NNMT inhibitors such as 5-amino-1MQ in experimental models

Journal of Physiology and Pharmacology

5 This can have significantly detrimental effects on the nervous system, cell division, and other methylation processes

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