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van der Meer 2013 Meer RM, Willemsen MC, Smit F, Cuijpers P

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Analytical chemist Ben Katz analyzed the composition of Zyn pouches and found that nicotine is the primary active ingredient, unlike other similar products that contain tobacco leaf

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[139] Since e-liquid production is not rigorously regulated, some e-liquids can have amounts of impurities higher compared to limits for pharmaceutical-grade nicotine products

The study authors recommend a range of interventions, including: A clear and scientifically supported federal definition of UPF, based on the NOVA classification system, that works for practical policy applications Front-of-pack labeling requirements and marketing restrictions, with a focus on child-targeted marketing Legal action by state attorneys general against food companies on behalf of the public, with settlement funds directed to health initiatives Institutional procurement and other policies that limit UPF and provide more minimally processed foods in places like schools