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Abbreviations: FDA Food and Drug Administration GDM gestational diabetes mellitus GLP-1 glucagon-like peptide-1

doi: 10.1186/s40170-020-00229-2 104 Galan-CoboASitthideatphaiboonPQuXPoteeteAPisegnaMATongPet al

Experiences from peptide receptor radionuclide therapy (PRRT), where diagnostic and therapeutic pairs such as 68 Ga/ 177 Lu-DOTA-exendin are co-developed, may offer valuable insights for designing biomarker-guided clinical trials in GLP-1R-targeted nanomedicine

Oxidation of Fatty Acids Is the Source of Increased Mitochondrial Reactive Oxygen Species Production in Kidney Cortical Tubules in Early Diabetes

A randomized, placebo-controlled dose-finding trial found that PT-141 produced an increase in the number of satisfying sexual events per month when self-administered subcutaneously at doses of 0.75, 1.25, or 1.75 mg over 12 weeks (Clayton et al., 2016)

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