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The vitamin C component might reduce the efficacy of these medicines

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Most patients describe the sensation as a brief pinch followed by mild pressure

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Signs of cobalamin deficiency in dogs A dog with cobalamin deficiency may have one or more of the following symptoms: Lethargy Loss of appetite Change in eating habits Dull coat Loss of muscle mass Weight loss Weakness Diarrhea Loss of interest in playing Failure to thrive Mental dullness Seizures Cobalamin deficiency in dogs primarily occurs when there is a problem with cobalamin absorption