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The temporary nature of most side effects contrasts sharply with the permanent benefits of achieving a healthy weight

N Engl J Med (2012) 367(3):21423

Nat Protoc (2011) 6(7):106083

No follow-up study has ever been published

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When to Call Your Provider While mild nausea is common, certain symptoms require prompt medical attention: Persistent vomiting or severe nausea Signs of dehydration (dizziness, dry mouth, reduced urine) Unexpected weight loss beyond goals Abdominal pain or other concerning symptoms Your MacArthur provider can adjust your dosage, suggest alternative timing, or provide supportive care to keep you on track safely