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Nicorandil's antifibrotic effects have been previously documented in bile duct ligation models, where treatment downregulated -SMA expression and improved hepatic architecture 33,34

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Controlled and structured lifestyle changes, including fasting diets combined with medicine, as in SheMed's Weight Loss Programme , tend to lead to better long-term results

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Those prescribed B12 replacement require follow-up to assess treatment response and determine ongoing requirements