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Sometimes it is an artifact of the assay itself

Intervention studies There are no intervention studies in individuals with vitamin B-12 insufficiency or deficiency that have assessed the effect of folic acid supplementation on serum holoTC concentrations, but 2 studies from the 1950s suggest there is an effect

It can be easily administered by a veterinarian or trained animal healthcare professional

Licensed 503A compounding pharmacies require provider oversight and prescriptions

Below that, you're paying for a compound diluted with synthesis byproducts

If someone is following a primarily vegan diet, they may not be getting enough B12 and might not be getting enough dairy. Calcium pills also tend to be really big and tedious, Cording says