Understanding the distinct and complementary contributions of each receptor system is essential to appreciating how mono-, dual-, and triple agonist formulations achieve their therapeutic effects [7-9,18,19] [Figure 1 and Table 1]
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Statistical analysis A sample size of 300 participants provided an effective power of at least 96% for the two co-primary endpoints, and at least 43% for all confirmatory secondary endpoints, which were tested in a predefined hierarchical order (Supplementary Table 4)
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Effect of piracetam on electrocorticogram and local cerebral glucose utilization in the rat