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Description

J Cardiovasc Pharmacol (2014) 64:4752

In der Reihe UNI-MED SCIENCE werden aktuelle Forschungsergebnisse zu Diagnostik und Therapie wichtiger Erkrankungen State of the Art dargestellt

F1000Res

Fumagalli, M

doi:10.1016/j.juro.2013.08.080 51

Comparison with the binding modes of other dual and triple agonists highlight that the N-terminal and C-terminal regions of the peptide confer receptor selectivity, whereas the middle region offers opportunities for sequence optimization to refine receptor engagement, thereby presenting a useful template for designing better unimolecular therapeutics