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Peripheral neuropathy applications including diabetic neuropathy, chemotherapy-induced neuropathy, and traumatic nerve injuries represent potential indications based on demonstrated nerve regeneration enhancement in animal models

Nature 626 (7998), 411418

This demonstrated that MBB is a substrate

These convergent pathways position mitochondrial failure, impaired proteostasis, and synaptic or axonal degeneration ahead of dopaminergic neuronal death in PD [10]

doi:10.1007/BF02978833

The dramatically increased half-maximal effective concentration of vitamin K (EC 50 ) required for carboxylation in DKO cells (~360-fold increase, 2.36 M vs 6.58 nM) (Fig