The proportion of patients who completed treatment with rescue medication varied across trials, but was consistently lower with oral semaglutide 7 mg, 14 mg, and flexibly dosed (026% across background medication subgroups) than comparator treatments (734%), whereas the proportion of patients who discontinued the trial product was often somewhat higher (1225% vs 515% except when sitagliptin was added to multiple background medications in PIONEER 7 [50% in a very small subgroup of 8 patients]) (see Table S1 in the Supplementary Information)
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As shown in Figure 12.10 and Table 12.2 , two molecules of ribulose 5-phosphate, the first pentose product of the redox stage, are converted into separate products: one molecule is isomerized to the aldose sugar ribose-5-phosphate, and the other is epimerized to xylulose-5-phosphate
J Trace Elem Med Biol Organ Soc Min Trace Elem (GMS)
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Retrieved from Yao, H., Zang, A., Li, D., et al