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These changes can all contribute to a healthier cardiovascular system, potentially lowering the risk of heart disease

51 Following this translocation, microbial-associated molecular patterns and damage-associated molecular patterns from stressed and damaged cells can enter the liver through the portal vein, activating immune and parenchymal cells on the surfaces of toll-like and nucleotide-binding oligomerization domain-like receptors, triggering inflammatory responses, promoting hepatic fat accumulation, and accelerating liver fibrosis

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Lovshin JA, Rajasekeran H, Lytvyn Y, Lovblom LE, Khan S, Alemu R, Locke A, Lai V, He H, Hittle L, Wang W, Drucker DJ, Cherney DZI

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Some patients experience dry skin or minor irritation as a secondary effect rather than a direct drug reaction