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Studies consistently show altered MGBA composition in AD patients, suggesting a possible role in disease onset and progression, as shown in Table 1

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The heterogeneity in this study was substantial, and we speculate that most of the heterogeneity may have come from clinical sources

After statistics, we found that the expression of these proteins decreased after PA modeling, and increased after adding berberine, while after giving GLP-1R inhibitor, this trend of berberine was inhibited (Figures 5CG)