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Mariani E, Ravaglia G, Forti P, Meneghetti A, Tarozzi A, Maioli F, et al

After 90 days, consider a follow-up test

When atorvastatin cocultured with RSL3, they appear to act synergistically in C2C12, but it was not enough for the synergy in HCM (Figure 3)

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Particularly, the pro-inflammatory cytokine TNF- is widely known to be a proximal mediator of hepatocyte apoptosis and necrosis in inflammatory DILI 48,49 , which could have contributed to hepatic injury in the model