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Molfino A, Cascino A, Conte C, Ramaccini C, Rossi Fanelli F, Laviano A: Caloric restriction and L-carnitine administration improves insulin sensitivity in patients with impaired glucose metabolism

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We should note that while we did not specifically quantify the MS lesions in these patients, clinical evaluation revealed no new lesions on any patient during the study and no obvious change in lesion volume

A compound affecting so many biological pathways could easily have subtler harms that small trials (or enthusiastic investigators) might miss

Yosipovitch G, Xiong GL, Haus E, Sackett-Lundeen L, Ashkenazi I, Maibach HI (1998) Time-dependent variations of the skin barrier function in humans: transepidermal water loss, stratum corneum hydration, skin surface pH, and skin temperature

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