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Medicare patients with a body mass index higher than 27, who have comorbidities such as cardiovascular disease or prediabetes, as well as patients with a BMI higher than 30, will be eligible for coverage of GLP-1 medications with a $50 copay each month for approved indications

Therapies such as ambroxol, a small molecule with lysosomal-enhancing properties, and buntanetap tartrate, a compound that can reduce neurotoxic protein levels, are some of the novel therapies currently under investigation for their potential to restore cellular balance and slow the progression of PD

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Notably, the trials also found that a lower starting dose (2 mg) during the dose-escalation phase could help mitigate the frequency and severity of these GI side effects, compared to a higher initial dose (4 mg)

Cognitive Behavioral Therapy for Insomnia (CBT-I)