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Ethics, reproducibility and methodological pitfalls Frequent pitfalls in cognitive peptide research No vehicle control in some old Russian studies: mandatory in any modern publication Non-randomisation : assigning animals to groups by order of arrival introduces systematic bias (weight, oestral cycle, cage stress) Non-blinded experimenter : behavioural tests are highly sensitive to expectations

Trager W, Jensen JB (1976) Human malaria parasites in continuous culture

A more stable, physiologically buffered glucagon solution is additionally attractive for potential use in a bi-hormonal pump for treatment of type 1 diabetes

There is an enhanced effect of corticosteroids in patients with hypothyroidism and in those with cirrhosis

Despite its relatively short half-life (2 4 hours), lixisenatide is recommended for once-daily dosing in the treatment of T2DM [ Table 2 ]

Nature 594 , 259264 (2021)